Duke vs. Syracuse Pick – February 5, 2025

The second-ranked Duke Blue Devils (19-2) have a respectable road test when they face the Syracuse Orange (10-12) on Wednesday, February 5 at 7:00 PM ET at the JMA Wireless Dome in Syracuse, New York. The Blue Devils are favored heavily to win with a point spread at -18.5 (-105) at MyBookie.

Duke Blue Devils Betting Preview

The Blue Devils have won their last 15 games led by star Cooper Flagg (20.0 PPG, 8.0 REB, 4.2 AST). Their most recent success was an 87-70 outing over the North Carolina Tar Heels where they also covered the 12.5-point spread.

Kon Knueppel led with 22 points, while Flagg stood out with 21 points, eight rebounds, and seven assists. The Blue Devils shot 52.8 percent from the field while making half of their three pointers.

Duke did a great job at getting to the foul line, as they made 21 out of 25 free throws, while the Tar Heels were 11-14. The Blue Devils also capitalized on turnovers, forcing the Tar Heels to commit 14 that resulted in 19 points.

The Blue Devils are putting up 80.3 points a game and making 47.7 percent of their shots from the floor. Their defense has held opponents to 60.0 points per game, which offers a beautiful margin of error when they are clicking on both ends of the floor.

Syracuse Orange Betting Preview

The Orange are coming off of a 75-66 win against the California Golden Bears. This victory snapped a three-game losing skid, which they have gone 2-3 in their last five games.

Syracuse had a big lead to end the first half, with a 40-23 performance. However, they were not as strong on the defensive end and allowed the Golden Bears to make it competitive with 43 points. Lucas Taylor led with 19 points on 62.5 percent shooting.

They made 46.3 percent of their shots and half of their three point attempts. On defense they did a great job at holding the Golden Bears to 28.6 percent shooting and 17.1 percent from deep. The Golden Bears did have an edge at the foul line, as they made 24 free throws while the Orange made 17.

The Orange are accumulating 74.2 points per game and are connecting on 45.4 percent of their shots. On defense they have given up 77.0 points per game, which shows a negative correlation between the two averages.

Odds, Series Trends, and Free Pick

The Duke Blue Devils vs. Syracuse Orange betting odds have been provided by MyBookie, showing the Blue Devils as 18.5-point favorites. The Blue Devils have a strong chance of winning this matchup, with a 92.9 percent chance of success according to market insights. The Blue Devils are too overpowered here and should be able to cover the spread.

Final Pick: Duke Blue Devils -18.5 (-105)