NCAA Tournament Spread Pick & Prediction: West Region – Memphis vs. Colorado State – Friday, March 21, 2025

A potential upset in the tournament that you should keep an eye on will be between the 12th-seed Colorado State Rams (25-9) and the fifth-seed Memphis Tigers (29-5) when they face off in the West Region on Friday, March 21 at 2:00 PM ET at Climate Pledge Arena in Seattle, Washington. Current betting odds from MyBookie reveal the Rams are slight favorites with a point spread at -1.5 (-115).

Colorado State Rams Betting Preview

The Rams have found success in their last 10 games, as they have not lost a game since mid-February. Their recent win was a 69-56 outing over the Boise State Broncos in the Mountain West Championship Final.

The success from the Rams has been primarily through Nique Clifford, as he leads them in several categories and really gets this team going. He currently leads with 19.0 points, 9.7 rebounds, and 4.4 assists each game.

Colorado State has been getting 75.2 points each game and ranking 137th in the country. On defense, they are allowing 67.1 points each game and ranking 45th. This spread is solid, but not a lot of breathing room.

The Rams are 51st overall for their strength of schedule and winning margins on teams. For each 100 possessions, their efficiency on offense ranks 76th while their defensive efficiency ranks 67th. This means they have a good shot at defeating some of the best teams in the nation, especially if they are locked in on both ends of the floor.

Memphis Tigers Betting Preview

The Tigers have won their previous eight games and carry great momentum heading into the tournament. They are coming off an 84-72 outing over the UAB Blazers in the American Athletic Conference Championship Final.

Production on both ends of the floor is key and Memphis has several players that can provide quality work. PJ Haggerty leads them with 21.8 points and shoots 48.4 percent from the field each game along with 3.8 assists. In addition, Dain Dainja contributes 14.4 points and 7.2 rebounds a game.

Memphis is getting 80.1 points each game and ranks 37th. Their defense is a bit troublesome as they allow 73.2 points a game and rank 220th. If they cannot defend well, they are at risk of losing this one.

The Tigers are 60th overall for their strength of schedule and point differential. Their efficiency on offense each 100 possessions ranks 94th while their defense at the same rate ranks 96th.

Odds, Series Trends, and Free Pick

MyBookie has you set with the best Colorado State Rams vs. Memphis Tigers betting odds. The Tigers have a 53.4 percent chance of winning per market analysis. The Rams are appealing to post the upset here and cover the speed.

Final Pick: Colorado State Rams -1.5 (-115)