Baltimore Orioles vs. Toronto Blue Jays Pick & Preview – March 27, 2025

The Baltimore Orioles and Toronto Blue Jays will battle in Game 1 of their four-game series when they face off on Thursday, March 27 at 3:07 PM ET at the Rogers Centre in Toronto, Ontario. MyBookie has the Orioles slightly favored with a run line at -1.5 (+145).

Baltimore Orioles Betting Preview

The Orioles went 91-71 and finished second in the AL East last year. They made it to the AL Wild Card Series but fell short in both matchups to the Kansas City Royals.

Gunnar Henderson led the team last season with a total of 177 hits, but will start the season off on the injured reserve list. Anthony Santander led with 44 home runs, but is now with the Toronto Blue Jays. In addition, Corbin Burnes led their pitching with 181 strikes, but is playing for the Arizona Diamondbacks.

Baltimore will have to show that they made the right adjustments heading into this season. While Henderson will be back in the lineup eventually, they are missing two key players from last season on both offense and defense.

The Orioles were second last season for appearances at the plate and home runs. They were third in slugging percentage and fourth in runs batted in. Overall, they were a strong offensive team.

Toronto Blue Jays Betting Preview

The Blue Jays capped off 2024 with a 74-88 record and fifth in the AL East. To put that in perspective, they finished 17 games behind the Orioles for second place (20 behind the leading New York Yankees).

Vladimir Guerrero Jr. led with 199 hits and 30 homers last season. Chris Bassitt was great on the mound with 168 strikes. They have a lot of work to do against their divisional rival compared to last season if they are looking to cover ground here.

Toronto needs help with their pitching, as well as the offensive end. Their off-season moves and some leading up to the season shows they have a lot of players in development but it might not translate until later in the season.

The Blue Jays were 18th in hits and 23rd for both runs and at bats. Their pitching ranked in the mid-20’s for about every category you could think of, showing how weak their consistency was for this aspect of their game.

Odds, Series Trends, and Free Pick

MyBookie offers the best Baltimore Orioles vs. Toronto Blue Jays betting odds. Current odds reveal the Orioles as 1.5-run line favorites. 

Both teams have made some adjustments from last season and the Orioles are aiming to fine-tune their roster to make a deeper playoff run. The Orioles are a little beat up and have lost some of their power on both sides of the ball, but should be able to cover the spread. 

Final Pick: Baltimore Orioles -1.5 (+145)