New York Mets vs. Houston Astros Pick & Prediction – March 28, 2025

The New York Mets and Houston Astros will battle in Game 2 of their three-game series on Friday, March 28 at 8:10 PM ET at the Fiserv Forum in Houston, Texas. MyBookie showcases the Astros with a run line at -1.5 (-235).

New York Mets Betting Preview

The Mets are coming off an 89-73 season last year and finished tied for second in the NL East. They were just six games back from the leading Philadelphia Phillies.

New York capped their season off in six games against the Los Angeles Dodgers in the NLCS. Some of these battles were lopsided affairs from both teams, but at least the Mets were able to do some damage in the postseason.

Francisco Lindor was their face for accumulating offense with 169 hits, while Pete Alonso also stood out with 34 home runs. Sean Manaea led their defense on the mound with 184 strikeouts. Tylor Megill is listed as the probable starter on the mound here.

The Mets shined in several categories on offense last season, ranking ninth in at bat appearances, seventh in runs, and 10th in hits. Their defense also had appealing performances such as fifth in strikeouts, 10th in innings pitched, and third in hits allowed. This could lead to a better season if they can make slight adjustments on both sides of the ball.

Houston Astros Betting Preview

The Astros may have finished first in the AL West, but fell short in the AL Wild Card to the Detroit Tigers after losing two games in a best-of-three series. While the games were somewhat closely contested, the Astros were left with a bitter taste and are aiming to make the right moves.

Houston only had a 3.5-game lead over the second place Seattle Mariners, which shows how tight this division can be. Getting off to a good start this season will show proof if they can make the necessary adjustments for a winning formula.

Looking at the stats, their offense was up and down and never provided the strength to push themselves further. They did show fourth in at bat appearances, third in hits, and 10th in home runs. Their defense stood out with sixth in ERA, fourth in hits allowed, and seventh in runs allowed.

Jose Altuve had 185 hits while Yordan Alvarez led with 35 homers. Hunter Brown was key to their success on the mound with 179 strikeouts. Brown is expected to start on the mound for this matchup. 

Odds, Series Trends, and Free Pick

MyBookie offers the best New York Mets vs. Houston Astros betting odds, which favor the Astors by 1.5 runs. A more appealing bet to make here would be under 8.5 runs, as the run line is a bit too heavy for the Astros to win by 1.5 runs.

Final Pick: Under 8.5 (-130)