Brentford vs Liverpool: Premier League Pick & Prediction, 25 October 2025
Revitalized after their five-star Champions League display on Wednesday, Liverpool return to domestic duty on Saturday night when Arne Slot’s side visit Brentford at the Gtech Community Stadium.
The Reds ended their four-game losing streak in emphatic fashion by thrashing Eintracht Frankfurt 5-1, but they now face a tricky Premier League test against a Brentford side brimming with confidence after a 2-0 victory over West Ham United.
Liverpool have dominated recent meetings between the clubs, winning each of their last five encounters, yet Brentford’s strong home record against top sides makes this an intriguing late-weekend clash in West London.
Head-to-Head History (H2H: Brentford vs Liverpool)
Since Brentford’s promotion to the Premier League in 2021, this fixture has delivered plenty of entertainment. It all started with a spectacular 3-3 draw in September 2021. The Bees lost just one of their first three league meetings with Liverpool (1-1-1), including a memorable 3-1 home win in January 2023.
However, Liverpool have since won five straight matches against Brentford, boasting an aggregate scoreline of 12-1. Their latest triumph came in January, when Darwin Nunez’s stoppage-time double secured a crucial 2-0 win at the Gtech Community Stadium.
Brentford: Current Form and Team News
After three consecutive league defeats on the road, Keith Andrews’ Brentford bounced back in style on Monday night, beating West Ham United 2-0 at the London Stadium. Goals from Igor Thiago and Mathias Jensen secured the Bees their first away league win of the season and their third overall.
The West London outfit sit 13th in the table on 10 points, five points clear of the relegation zone and just as many behind their visitors. Still, their home form remains inconsistent – just five wins in 16 matches at the Gtech Community Stadium in 2025 (5-4-7).
Injuries continue to challenge Andrews’ squad. Paris Maghoma and Antoni Milambo remain sidelined, while Aaron Hickey faces a late fitness test after missing the West Ham clash. Former Liverpool trio Caoimhin Kelleher, Sepp van den Berg and Jordan Henderson are all expected to start against their old club, while Keane Lewis-Potter may return to the left wing-back role if Andrews opts for a back five.
Leading scorer Igor Thiago, who has netted five league goals, should spearhead the attack once again, potentially alongside Kevin Schade or Dango Ouattara should Andrews opt for a more conservative approach.
Liverpool: Current Form and Team News
Liverpool’s midweek performance in Frankfurt was exactly what Arne Slot needed after enduring the worst run of his tenure – four consecutive defeats across all competitions, including a 2-1 loss to bitter rivals Manchester United at Anfield last weekend.
The 5-1 demolition of Eintracht Frankfurt, courtesy of goals from Hugo Ekitike, Virgil van Dijk, Ibrahima Konate, Cody Gakpo and Dominik Szoboszlai – lifted morale and ended the Reds’ longest losing streak since 2014. Still, defensive issues remain a concern, with 18 goals conceded in 13 matches this season.
In the Premier League, Liverpool have lost three of their last four away games, including all four of their most recent trips to London – a pattern Slot will be desperate to end as the reigning champions chase the top two.
On the injury front, Slot has confirmed that Ryan Gravenberch and Alexander Isak are both doubts for Saturday’s visit to Brentford, while Jeremie Frimpong has suffered a long-term setback and will be sidelined for a prolonged period. Meanwhile, first-choice goalkeeper Alisson and summer signing Giovanni Leoni remain out of contention for the Merseysiders.
The Reds will be hopeful that at least Gravenberch can recover in time to feature in midfield, potentially alongside Alexis Mac Allister. Mohamed Salah, still searching for his first open-play goal in seven Premier League matches, could return to the starting lineup, while Florian Wirtz – who registered two assists off the bench in midweek – is pushing for inclusion as well.
Tactical Duel: Keith Andrews vs Arne Slot
Keith Andrews will likely rely on a compact 5-3-2 formation designed to frustrate Liverpool’s midfield rhythm. Expect former Liverpool captain Henderson to sit deep, orchestrating transitions while Igor Thiago’s physical presence tests the Reds’ vulnerable backline. Brentford’s wing-backs, particularly Lewis-Potter, could be key outlets in transition, aiming to exploit space behind Liverpool’s usually advanced full-backs.
Meanwhile, Arne Slot is expected to maintain Liverpool’s attacking 4-2-3-1 system, pressing high and looking to overload the wide areas. Szoboszlai’s late runs and Gakpo’s versatility could trouble Brentford’s defensive shape, while Salah and Ekitike will look to stretch the Bees with movement across the front line.
Possible Starting Lineups of Brentford and Liverpool
Brentford: Caoimhin Kelleher – Michael Kayode, Nathan Collins, Sepp van den Berg, Kristoffer Ajer, Keane Lewis-Potter – Jordan Henderson, Yehor Yarmoliuk, Mikkel Damsgaard – Kevin Schade, Igor Thiago. (5-3-2)
Liverpool: Giorgi Mamardashvili – Dominik Szoboszlai, Ibrahima Konate, Virgil van Dijk, Milos Kerkez – Curtis Jones, Alexis Mac Allister – Mohamed Salah, Florian Wirtz, Cody Gakpo – Hugo Ekitike. (4-2-3-1)
Brentford vs Liverpool Betting Prediction and Odds
According to the latest betting odds from EveryGame, Liverpool are -137 favorites to return to winning ways in Premier League action, while Brentford’s home odds and the draw are both priced at +320.
The numbers clearly underline Liverpool’s superiority, but Brentford’s resilience at home simply cannot be ignored. The Bees have scored in nine of their 10 matches this season across all competitions (apart from the 1-0 home loss to Manchester City earlier this month), while the Reds have found the net in all eight of their Premier League meetings with Brentford – their second-best 100% scoring record against any opponent.
Given the form of both sides and Liverpool’s ongoing defensive vulnerability, goals at both ends look highly likely. However, the Merseysiders’ superior firepower should eventually be unleashed.
For those seeking additional value, Brentford’s Igor Thiago Anytime Goalscorer bet at +190 also stands out, while Mohamed Salah (+120) and Hugo Ekitike (+130) remain the most likely scorers for the Reds, should Alexander Isak fail to prove his fitness – the Swede is currently priced at +100.