2025 Mens US Open Predictions

Félix Auger-Aliassime vs Alex de Minaur Best Bet & Prediction, US Open – September 3, 2025

The US Open men’s competition is nearing its climax with a compelling quarterfinal clash between two players on contrasting trajectories. Felix Auger-Aliassime, the resurgent Canadian rediscovering his best form after years of inconsistency, takes on Alex de Minaur, the relentless Australian who has established himself as one of the most reliable performers on the ATP Tour over the past two seasons.

Both men are chasing their maiden Grand Slam final, and with either Jannik Sinner or Lorenzo Musetti awaiting in the semifinals, this matchup carries even greater weight as a potential launching pad toward a career-defining breakthrough.

Head-to-Head and Matchup Dynamics (H2H: Auger-Aliassime vs De Minaur)

The head-to-head favors the Canadian, who leads 3-2. However, this will be their first-ever Grand Slam match and three of their past five encounters were either at Challenger events (in 2017 and 2018) or a Davis Cup match in 2022.

While Alex de Minaur’s consistency and athleticism give him a slight edge with bookmakers, Felix Auger-Aliassime’s ceiling is significantly higher. If the Canadian lands his first serve and keeps his forehand under control, he has the weapons to dictate rallies and break through the Australian’s defense. On the other hand, any dip in level will play directly into the Australian’s hands, who thrives on extended rallies and forcing errors.

Alex de Minaur: Building on Relentless Consistency

Alex de Minaur has arrived in the quarterfinals (his third appearance at this stage in New York) with confidence and efficiency, benefiting from a favorable draw and making the most of it. In the last-16, the 26-year-old Australian dismantled US Open debutant Leandro Riedi (ranked 435th) in just one hour and 35 minutes, conceding only six games in a 6-3, 6-2, 6-1 victory. Across his first four matches, he has dropped just one set (in his third-round victory over Daniel Altmaier of Germany, who won the opening set) conserving precious energy for the challenges ahead.

This is a continuation of de Minaur’s transformation into one of the most reliable Slam performers outside the current tennis’ dominant trio. The Australian is now contesting his fifth Grand Slam quarterfinal in his last seven majors, an impressive level of consistency surpassed only by Novak Djokovic, Carlos Alcaraz and Jannik Sinner. Furthermore, Alex de Minaur is the first Australian since Lleyton Hewitt more than 20 years ago to reach back-to-back US Open quarterfinals.

Yet, the main question remains: can The Demon finally break through this stage? He has played four Slam quarterfinals and lost all of them in straight sets, three to top-five players. His challenge now is to convert consistency into true contention – something which Andrey Rublev failed to do when the Russian lost yet another Major quarter-final – this time to Auger-Aliassime.

Felix Auger-Aliassime: A Long-Awaited Canadian Revival

For the 25-year-old Canadian, this run feels like a career reset. After nearly four years without a Grand Slam quarterfinal, Felix Auger-Aliassime has finally delivered on his potential, knocking out big names along the way. His most impressive moment came in the third round, when he stunned World No. 3 Alexander Zverev in four sets, his first-ever top-five win at a Grand Slam. Auger-Aliassime backed it up with another top-quality performance, defeating 15th-seed Andrey Rublev to return to the last eight at Flushing Meadows.

With this surge, FAA is projected to climb back into the ATP Top 20, restoring confidence after a prolonged dip in form. Auger-Aliassime has often been labeled an underachiever, but his career achievements still surpass most of his peers, and this breakthrough could be the spark to realign his career trajectory. Interestingly, among players born in the 2000s, only Alcaraz and Sinner have reached more Major quarterfinals than him.

The Canadian’s Grand Slam history has been filled with heartbreaks, none more painful than the 2022 Australian Open quarterfinal, where he squandered a two-set lead and a match point against Daniil Medvedev. His record in Major quarterfinals stands at 1-2, his lone success coming at the 2021 US Open when Carlos Alcaraz retired during the second set. This chance to rewrite his Slam narrative adds another layer of motivation.

Betting Prediction and Odds

According to EveryGame‘s latest betting odds, de Minaur enters as the -154 favorite, while Auger-Aliassime sits as a +120 underdog despite his strong performances against Zverev and Rublev. The Total Games line is set at 38.5 (-118 each way), and the matchup profile strongly supports the Over 38.5 line. De Minaur’s unmatched consistency across long exchanges and Auger-Aliassime’s offensive peaks suggest a match that could stretch into four or five sets.

While The Demon is the favorite (we already backed Alex de Minaur to Win the Second Quarter at +425 in our 2025 US Open Betting Preview), Auger-Aliassime’s resurgence and history of pushing big matches deep make this a potential thriller. Therefore, Over 38.5 Games looks the most solid pick for this quarter-final clash.

Felix Auger-Aliassime vs Alex de Minaur Best Bet: Over 38.5 Games (-118) at EveryGame for 6/10 Units